In addition, the information available in the literature does not account for the steroid type or dose, as neither could additionally be identified. Patients additionally may be taking concomitant stimulants, similar to ephedra, which can confound data and the potential for adverse events. It is likely that the frequency of cardiac occasions is underreported in the medical literature. Supraphysiologic doses of anabolic-androgenic steroids , which include more than 30 natural and synthetic derivatives of testosterone, could cause a wide spectrum of scientific sequalae.
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- Relationship between endogenous sex hormone ranges, lipoproteins and coronary atherosclerosis in men undergoing coronary angiography.
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However, testosterone in physiologic doses may even be useful in patients with angina , have larger ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood move in men with established coronary artery disease . Therefore, an interplay of endogenous elements of the patient’s threat profile in addition to the testosterone dosing may be issues of whether or not adverse occasions occur. Erythrocytosis has been reported as a possible effect of testosterone, which could be useful in patients with anemia. The greatest threat of erythrocytosis happens with injectable forms of testosterone in contrast with transdermal preparations, especially in supraphysiologic doses. An enhance of as much as 44% of the baseline hematocrit has been reported . Moreover, testosterone has been used in the treatment of decreased muscle mass and bone density in addition to anemia.
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